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Kajian Docking Molekular Pada Binding Site Pocket Dari Flavopiridol Dalam Menghambat Glikogen Fosforilase Menggunakan Pyrx-Autodock-Vina
(STIKES Muhammadiyah Pekajangan, 2016-08-27)
nhibition of the enzyme glycogen phosphorylase which break down glycogen into glucose 1- phosphate (glycogenolysis) is a target in the treatment of type 2 diabetes milletus. Interaction mechanism between glycogen phosphorylase ...
Identifikasi Agen Antidiabetes Melalui Jalur Penghambatan Aldose Reductase Menggunakan Pyrxdengan Empat Algoritma Molecular Docking
(STIKES Muhammadiyah Pekajangan, 2016-08-27)
Aldosereductaseisaldo-ketoreductaseenzyme that convert glucoseto sorbitol and fructosebypolyolpathway. Accumulation of sorbitol andoxidative stress dueto changes in the ratio of NADPH/NADP+ and NADH/NAD+ cause some ...