| dc.identifier.citation | ACC/SCN. 2001. What Works? A Review Of The Efficacy And Effectiveness Of Nutrition Interventions. ACC/SCN Nutrition Policy Paper 19, Allen, L, Gillespie, S. (Ed.), Geneva. Beard, JL. 2001. Iron biology in immune function, muscle metabolism and neuronal funtioning. J Nutr. 131(2S-2); 568S-579S; discussion 580S. Beard, J. 2003. Iron Deficiency Alters Brain Development and Functioning J. Nutr. 133: 1468S– 1472S. Bhaskaram, P. 2001. Immunobiology of mild micronutrient deficiencies. Br J Nutr. 85 Suppl 2:S75-80. Black RE. 2003. Zinc deficiency, infectious diseases and mortality in the developing world. J Nutr; 133:1485S-9S. Black, MM., Baqui, AH., Zaman, K. 2004. Iron and zinc supplementation promote motor development and explatory behavior among Bangladesh infants. Am J Clin Nutr: 68(suppl) 80:903-10. Desai, MR., et al. 2004. Daily Iron Supplementation Is More Efficacious than Twice Weekly Iron Supplementation for the Treatment of Childhood Anemia in Western Kenya1-3. J. Nutr. 134: 1167–1174. De Silva A., et al. 2003. Iron supplementation status and reduces morbidity in children with or withour upper respiratory tract infections: a randomized controlled study in Colombo, Srinlanka. Am J Clin Nut. 77(1): 234-41. Gillispie S. 1998. Major Issues in The Control of Iron Deficiency. The Micronutrient Initiative. UNICEF, New York Hadi, H. 2001. Meningkatkan kepatuhan minum tablet besi ibu hamil: pentingnya peranan suami. Berita Kedokteran Masyarakat XVII (2) : 51-62. Hamadani , JD., et al. 2001. Randomized controlled trial of the effect of zinc supplementation on the mental development of Bangladeshi infants. Am J Clin Nutr; 74:381-6. Hidayati, L., Dasuki, MS., Prasetyaningrum, J. 2005. Efek Suplementasi Fe dan Zn terhadap pertumbuhan dan perkembangan anak : Uji Klinis Acak Terkontrol di Kabupaten Bantul. Hasil penelitian yang tidak dipublikasikan. Idjradinata, P., Pollit, E. 1993. Reversal of developmental delays in iron-deficient anemic infants treated with iron. Lancet; 431: 1-4. Lind T., et al. 2003. A community-based randomized controlled trial of iron and zinc supplementation in Indonesian infants: interactions between iron and zinc. Am J Clin Nutr; 77:883-90. Munoz, EC., et al. 2000. Iron and zinc supplementation improves indicators of vitamin A status of Mexican preschoolers. Am J Clin Nut. 71(3): 789-94. Murray, RK., et al. 1996. Harper’s Biochemistry (14th ed.) Appliton & Lange, Stanford-Connecticut. Muslimatun, S. 2001. Nutrition of Indonesian women during pregnancy and lactation: a focus on vitamin A and Iron. Wageningen University. Thesis. Oppenheimer, SJ. 2001. Iron and its relation to immunity and infectious disease. J Nutr, 131(2S- 2):616S-633S; discussion 633S-635S. Rico, JA., et al. 2006. Efficacy of Iron and/or Zinc Supplementation on cognitive performance of Lead-Exposed Mexican Schoolchildren: A Randomized, Placebo-Controlled Trial. Pediatrics: 117;518-527 Schmidt, MK. 2001. The role of maternal nutrition in growth and helath of Indonesian infants: a focus on vitmain A and Iron. Wageningen University. Thesis. Stoltzfus, RJ. 2001. Iron-deficiency anemia: reexamining the nature and magnitude of the public health problem. Summary: implication for research and programs. J Nutr, 131:697S-700S; discussion 700S-1S. (Abstract). Sungthong, R., et al. 2004. Once-Weekly and 5-Days a Week Iron Supplementation Differentially Affect Cognitive Function but Not School Performance in Thai Children. J. Nutr. 134: 2349–2354. Smuts,CM., et al. 2005. Efficacy of a Foodlet-Based Multiple Micronutrient Supplement for Preventing Growth Faltering, Anemia, and Micronutrient Deficiency of Infants: The Four Country IRIS Trial Pooled Data Analysis. J. Nutr. 135: 631S–638S. Zlotkin, S., et al. 2003. Home-fortification with iron and zinc sprinkles or iron sprinkles alone successfully treats anemia in infants and young children. Am J Clin Nutr; 133(4): 1075-80. | en_US |
| dc.description.abstract | The long term objective of this research is to increase the quality of human resources in Indonesia,
especially the students of elementary school who suffer anemia. Furthermore, the focused target of such a
research is to find an effective as well as safe model of Fe and Zn supplementation to: (1) increase the
content of Hb, (2) accelerate the growth (the nutrition status), and (3) improve the cognitive development of
the anemic elementary school students.
In the second year, the research design is Randomized Control Trial double blinded. With this design, the
research subjects were randomly divided into two treatment groups, i.e. (1) one group had 10 mg Fe in the
form of candy once a day; (2) the other group had 10 mg Fe and Zn in the form of candy once a day.
The results of the study show that a significant difference occurs between the content of Hb before and
after the supplementation either Fe candy or a combination of Fe and Zn candy (p=0,0001). However, No
significant difference happens between the two treatments (p=0,5346). There is a significant difference
between the nutrition status before and after the Fe candy and Fe+Zn candy supplements (p=0,020), but
there is no difference between the two treatments (p=0,078). The findings also demonstrate that there is
no difference on the level of cognitive development to happen between the two treatments (p=0,649).
The supplement in the form of candy is recommended as one alternative of supplement except for syrup
and pills. The substance combination candy is more suggested to give than the single substance one.
Moreover once-a-day treatment is also recommended for the students. | en_US |
