Aphrodisiac Effect of Lunasia amara Blanco, Centella asiatica and Curcuma domestica Combination Infusion on Male Rat Libido

Abstract

Sanrego (Lunasia amara Blanco) is a plant having stimulant effect on nervous cell and ability toimprove health of body system. Preliminary study showed that methanol extract of Lunasia amara Blanco wood at a dose administration of 10 mg/200 g body weight had aphrodisiac effect in Wistar white rat. Centella asiatica and Curcuma domestica have role as excipient. The objective of this research was to determine the aphrodisiac effect of the infusion of Lunasia amara Blanco, Centella asiatica and Curcuma domestica on strain SD rats. The frequencies of introduction, climbing and coitus of male rats were counted as aphrodisiac effect parameter. The concentrations of pre- and post-treatment of male rat testosterone hormone were determined using rat testosterone ELISA kit. There were significant differences of introduction (P=0.019) and coitus (P=0.042) frequencies between male rat group which administered by combination infusion of Lunasia amara Blanco, Centella asiatica and Curcuma domestica and group was not given. There was no significant difference between the testosterone levels of male rat group administered by combination infusion and group that was not given the infusion (P=0.107). The combination infusion of Lunasia amara Blanco, Centella asiatica and Curcuma domestica had aphrodisiac effect on male Sprague-Dawley rats libido.