EFEKTIVITAS WAKTU FLUOXETINE TERHADAP RESPON IMUN LEVEL CD4 PADA TIKUS PUTIH GALUR WISTAR DENGAN DEPRESI AKUT

Abstract

Depressed patients need mental therapy to improve their condition and prevent serious mental disorder in the future. Patients with depression have sign and symptom such as decrease of immune system and inability to manage problems. Furthermore, they will have serious depression. Fuoxetine can be used to improve the number of body immune and resolve depression symptom. Flouxetine is usualy given for 4 until 8 weeks. The aim of this research was to investigate the most effective fluoxetine time to CD4 level at the depressed wistar mice. Research design used experiment with randomized control method. Samples of the research were 20 wistar mouses includes experiment and control group. The data analysis used hotteling traces to determine effectiveness fluoxetine time. The result of the data analysis showed the mean of CD4 score of the group which were given fluoxetine was highest at third week than the other groups.