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dc.contributor.authorM., Muhtadi
dc.date.accessioned2012-03-12T06:52:36Z
dc.date.available2012-03-12T06:52:36Z
dc.date.issued2008-10
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dc.identifier.issn1411-5174
dc.identifier.urihttp://hdl.handle.net/11617/420
dc.description.abstractTelah dilakukan penelitian untuk mengamati aktivitas antiplasmodium dari ekstrak metanol kulit kayu mimba (Azadirachta indica). Fraksi yang diamati adalah fraksi nonpolar, semipolar dan polar yang diperoleh dengan metode kromatografi cair vakum dengan eluen n-heksana-etilasetat. Hasil penelitian menunjukkan bahwa fraksi nonpolar memiliki aktivitas antiplasmodium yang paling tinggi terhadap P. falciparum strain D10 secara in vitro, dengan nilai IC50 6,23 ìg/mL, sedangkan fraksi semipolar dan polar memiliki aktivitas antiplasmodium yang makin menurun, dengan nilai IC50 masing-masing 10,25 dan 11,37 mg/mL. Hasil analisis KLT dan uji fitokimia menunjukkan bahwa fraksi nonpolar dan semipolar memiliki kandungan senyawa kelompok triterpenoid, alkaloid dan flavonoid, sedangkan fraksi polar hanya teridentifikasi adanya senyawa flavonoid. Aktivitas antiplasmodium sangat dipengaruhi oleh keberadaan senyawa-senyawa nonpolar (triterpenoid).en_US
dc.subjectAzadirachta indicaen_US
dc.subjectaktivitas antiplasmodiumen_US
dc.subjectP. falciparum strain D10en_US
dc.titlePEMISAHAN FRAKSI DAN SENYAWA-SENYAWA YANG BERKHASIAT ANTIPLASMODIUM DARI EKSTRAK METANOL KULIT KAYU MIMBA ( Azadirachta indica Juss)en_US
dc.title.alternativeTHE SEPARATION OF COMPOUNDS AND FRACTION VIRTUING ANTIPLASMODIUM FROM METHANOL EXTRACTS OF MIMBA TREE BAR ( Azadirachta indica Juss)en_US
dc.typeArticleen_US


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