| dc.identifier.citation | 1. Chen, J.J. et al.2004, Flavones and Cytotoxic Constituents from the Stem Bark of Muntingia calabura, Jurnal of Chinese Society.665-670. 2. Lee, 2004, Studies on the chemical and cytotoxic constituent from the leaves of muntingia calabura and the stem woods of zanthoxylum pistaciiflorum, thesis, graduate institute of pharmaceutical technologi, Taiwan. 3. Lin.F,-L , J.-j Chen, C.D, Shih, 2005, Antinociceptive and anti-inflammatory activity of the water-soluble extracts from leaves of Muntingia cabura, Jurnal of Chinese Society. 4. Premakumari KB, Siddiqua A., Sultana R, Vithya and Savitha, 2000. Antioxidant Activity and Estimation of Total Phenolik Content of Muntingia calabura by Colorimetry, Internastional Journal of Chem Tech Research, 205-208. 5. Preethi, K. , Premasudha, P. , Keerthana, K., 2012, Antiinflammatory activity of Muntingia calabura fruits, Department of Microbial Biotechnology, Bharathiar University, Coimbatore - 641 046, Tamilnadu, India. | en_US |
| dc.description.abstract | Inflammation is a local protective response resulting from trauma or damage in the tissue
functioning to destroy or to reduce injury agent or injured antigen. The objective of study was to
compare the anti-inflammatory effect of unripe Mutingia calabura L, ripe Mutingia calabura L
fruits and Mutingia calabura L leaves in Wistar white rat on anti-inflammation. The antiinflammatory
effect testing was carried out using 8 rats per group, each of which was treated
with karagenan induction. Each group was given treatment: the first group was given 1%
CMCNa, the second group was given Na-diclophenac, the third unripe Mutingia calabura L
was given fruit extract 50 mg/kg BW, the fourth group was given unripe Mutingia calabura L
fruit extract 100 mg/kg BW, the fifth group was given ripe Mutingia calabura L fruit extract 50
mg/kg BW, the sixth group was given ripe Mutingia calabura L fruit extract 100 mg/kg BW, the
seventh group was given Mutingia calabura L leaves 50 mg/kg BW, and the eighth group was
given Mutingia calabura L leaves 100 mg/kg BW. The reserch to know anti inflammatory
activity of Muntingia calabura L. unripe, ripe fruits and leaves ethanol extract of carrageenan
induced rat paw edema, percentage (%) of anti inflamatory of ethanol extract of Muntingia
calabura L. unripe, ripe fruits and leaves, and effect of Muntingia calabura L. unripe, ripe
fruits and leaves on carragenan induced inflamasi change of inflammatory inhibition
percentage (%). The result showed that unripe Mutingia calabura L, ripe Mutingia calabura L
fruits, and Mutingia calabura L leaves groups had a significantly different anti-inflammatory
effect compared to Na-diclophenac in inhibiting edema volume in male white rat. | en_US |
