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| dc.description.abstract | Mangosteen rind (Garcinia mangostana l) is one of plant herbal simplicia have contain
substance active discover good killed of bacterial like flavonoids, xanthone, tannin, terpenoid,
and saponin. Mangosteen rind is one of plant that have a potency to use as a drugs too. The
research purpose to find the inhbiting activity of the ethanol extract of mangosteen rind against
the Escherichia coli and Staphylococcus aureus growth. This study used laboratory
experimental research design true experimental with post test only control group design
method. The ethanol extract of mangosteen rind is tested by well method with concentration
5%, 10%, 20%, 40%, 60%, and 80% w/v. Wells is made on Muller Hinton germ growth media
which is smeared by culture of Escherichia coli ATCC 11229 and Staphylococcus aureus ATCC
6538 which has been standardized by Mc Farland. The ethanol extract of mangosteen rind drip
in to the well with various concentration. It is incubated with a temperature of 37
c for 24 hours
and inhibition of zone radical is measured by Vernier caliper. The ethanol extract of
mangosteen rind (with concentration 5%, 10%, 20%, 40%, 60%, and 80% w/v, can inhibit the
growth Staphylococcus aureus whit mean inhibition zone diameter is 10,6 mm, 12,6 mm, 14,8
mm, 15 mm, 15,8 mm, and 16,8 mm. The velue of statistic Kurskall Wallis test 0,000. While
Escherichia coli the extract of mangosteen rind can’t inhibition zone and the velue of statistic
Kurskall Wallis test unknown. The ethanol extract of mangosteen rind has antibacterial activity
against Staphylococcus aureus ATCC 6538 in vitro | en_US |
