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Comparison of Antibacterial Activity of Ethanolic Extracts of Seed and Stem Papaya (Carica Papaya l.) Against Shigella Dysenteriae and Streptococcus Pyogenes

dc.contributor.authorCristiana, Yeni
dc.contributor.authorYuliani, Ratna
dc.date.accessioned2015-03-19T07:47:32Z
dc.date.available2015-03-19T07:47:32Z
dc.date.issued2015-01
dc.identifier.citationHamman, W. O., Musa, S. A., Ikyembe, D.T., Umana U.E., Adelaiye, A.B., Nok, A.J., et al., 2011, Ethanol Extract of Carica papaya Seeds Induces Reversible Contraception in Adult Male Wistar Rats, British Journal of Pharmacology and Toxicology, 2 (5), 257-261. Khan, J. A., Yadav, J., Srivastava, Y. & Pal, P. K., 2012, In Vitro Evaluation Of Antimicrobial Properties Of Carica papaya L., International Journal of Biology, Pharmacy and Allied Sciences, 1 (7), 933-945. Nayak, B. S., Ramdeen, R., Adogwa, A., Ramsubhag, A., & Marshall, J. R., 2012, Wound- Healing Potential of an Ethanol Extract of Carica Papaya (Caricaceae) Seeds, International Wound Journal, 1-6. Okoye, E. I., 2011, Preliminary Phytochemical Analysis And Antimicrobial Activity Of Seeds Of Carica papaya, Journal of Basic Physical Research, 2 (1), 66-69. Radji, M., 2009, Buku Ajar Mikrobiologi: Panduan Mahasiswa Farmasi dan Kedokteran, 139, 156, Jakarta, EGC. Saidu, A. N., & Nweri, C. G., 2013, Phytochemical Screening and Effects of Methanol Extract of Carica papaya Stem bark in alloxan induced Diabetic Rats, Journal of Emerging Trends in Engineering and Applied Sciences, 4 (6), 819-822 Sears, B. W., Spear, L. & Saenz, R., 2011, Intisari Mikrobiologi & Imunologi, diterjemahkan oleh Hartono, A., 120, Jakarta, EGC. Setyawan, W., 2009, Aktivitas Antibakteri Ekstrak Etanol Batang Pepaya (Carica papaya L.) terhadap Staphylococcus aureus dan Escherichia coli Multiresisten Antibiotik, Skripsi, Fakultas Farmasi Universitas Muhammadiyah Surakarta. Stephen, C., Ukpabi, C., EsiheTochukwu, E., Brown, N., 2013, Chemical Composition Of Carica papaya Stem (Paw-Paw), American Open Food Science Journal, 1 (1), 1-5. Sears, B. W., Spear, L. & Saenz, R., 2011, Intisari Mikrobiologi & Imunologi, diterjemahkan oleh Hartono, A., 120, Jakarta, EGC. Tambayong, J., 2000, Mikrobiologi untuk Keperawatan, 3, 26, 45, Jakarta, Widya Medika. Wagner, H. & Bladt, S., 1996, Plant Drug Analysis: A Thin Layer Chromatography Atlas, 2nd edition, Germany, Springer.in_ID
dc.identifier.isbn978-602-70429-9-5
dc.identifier.urihttp://hdl.handle.net/11617/5412
dc.description.abstractGenerally, seed and stem of papaya (Carica papaya L.) are not used. In a previous study, seed and stem of papaya inhibit growth of Escherichia coli and Staphylococcus aureus. The aim of this study was to compare antibacterial activity of ethanolic extract of papaya seed to stem extract against Shigella dysenteriae and Streptococcus pyogenes. Papaya seed and stem were extracted using 70% ethanol by maceration method. The antibacterial activity tests were carried out using Kirby-Bauer disk diffusion method. Chemical compounds in the extracts were identified using thin layer chromatography (TLC) with silica GF254 as stationary phase and a mobile phase of ethyl acetate : methanol : water (100 : 13 : 17)v/v for papaya seed extract and methanol:chloroform (8:2)v/v for papaya stem extract. The results showed that ethanolic extract of papaya seed and stem have same antibacterial activity against Shigella dysenteriae and Streptococcus pyogenes. Based on TLC analysis, papaya seed contain alkaloid, steroid, and tannin, while papaya stem contain tannin.in_ID
dc.language.isoenin_ID
dc.publisherUniversitas Muhammadiyah Surakartain_ID
dc.subjectpapaya (Carica papaya L.)in_ID
dc.subjectantibacterialin_ID
dc.subjectShigella dysenteriaein_ID
dc.subjectStreptococcus pyogenesin_ID
dc.titleComparison of Antibacterial Activity of Ethanolic Extracts of Seed and Stem Papaya (Carica Papaya l.) Against Shigella Dysenteriae and Streptococcus Pyogenesin_ID
dc.typeArticlein_ID


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