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dc.contributor.authorHaryoto
dc.contributor.authorIrjayanti, Anis Novida
dc.contributor.authorSuhendi, Andi
dc.contributor.authorMuhtadi
dc.contributor.authorSujono, Tanti Azizah
dc.date.accessioned2015-10-30T04:26:14Z
dc.date.available2015-10-30T04:26:14Z
dc.date.issued2015-10-30
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dc.identifier.issn9-772476-969006
dc.identifier.urihttp://hdl.handle.net/11617/6192
dc.description.abstractEthanol extract of the leaves salaplant (CynometraramifloraLinn.) have cytotoxic activity against WiDr cells with IC50 of 6.37 μg/mL. This study aims to determine the cytotoxic activity of polar, semipolar, and nonpolar fractions of ethanol extract of leaves sala plant (CynometraramifloraLinn.) against WiDr cells. Fractionation was performed on Vacuum Liquid Chromatography method with silica G 60 as stationary phase and n-hexane: ethylacetate(8:2; 7.5:2.5; 7:3,6:4 and 3:7) and ethanol as mobile phase. Qualitative screening of major compounds used TLC method with spray reagent. Cytotoxicity determination performedin vitro model cell lines with MTTreagent.The result showed that IC50 of polar, semi polar and non polar fractions were 231.95 μg/mL and cannot determined. Doxorubicin was used as positive control and obtained IC50 of 1.721 μg/mL.in_ID
dc.language.isoenin_ID
dc.publisherUniversitas Muhammadiyah Surakartain_ID
dc.subjectCytotoxicin_ID
dc.subjectMTT assayin_ID
dc.subjectCynometra ramiflorain_ID
dc.subjectWiDr cellin_ID
dc.subjectIC50in_ID
dc.titleCYTOTOXIC ACTIVITY OF POLAR, SEMIPOLAR, AND NON POLAR FRACTION OF ETHANOL EXTRACT OF SALA PLANTS LEAVES (Cynometra ramiflora Linn.) AGAINTS WiDr CELLin_ID
dc.typeArticlein_ID


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    Current Breakthrough in Pharmacy Materials and Analyses

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