The Effectiveness Of Tempuyung Leaf (Sonchus Arvensis) Decoction in Lowering Total Cholesterol Of Male Rats (Rattus Novergicus)
View/ Open
Date
2016-05-27Author
Kimo, Zulyamin
Fitriyani, Titin
Zahra, Fatimatuz
Vitria, Vanis
Nurwahida
Metadata
Show full item recordAbstract
Cholesterol levels in the blood can have varied suggestions. If the LDL levels in the body are
high, it will harm our body, especially the cholesterol blockage of blood vessels. The
compilation of the WHO Global status report on non-communicable diseases in 2008 showed
that the prevalence of risk factors of hypercholesterolemia in Indonesia women was higher at
37.2% compared to men’s, which was only 32.8%. There are many ways to minimize the
danger of cholesterol, one of them is by eating vegetables, herbs or wild plants that are
efficacious in lowering cholesterol levels in the body. One of the wild plants, which have the
potential to lower cholesterol level, is tempuyung leaves (Sonchus arvensis). Based on the
studies that had been conducted before, tempuyung leaves had the benefit to lower uric acid
levels in rats, dissolve calcium oxalate. Tempuyung leaves contain flavonoid amounted to
0.1044% that can act to reduce LDL in the body. This study was an experimental study (true
experimental research), which aimed to determine whether tempuyung leaf (Sonchus
arvensis) decoction is effective in lowering the total cholesterol levels in male rats. The
samples used were four white rats (Rattus novergicus), rat as the negative control treatment
has absorbance value of 0.058 with total cholesterol level of 59.183 mg/100g. Rat as the
positive control treatment has absorbance value of 0.090 with total cholesterol level of 91.836
mg/100g. The decoction of tempuyung leaves concentration of 20% has absorbance value of
0.122 with total cholesterol of 183.163 mg /100 g. The decoction tempuyung concentration of
40% has absorbance value of 0.225 with total cholesterol level of 340.414 mg /100 g. The
results of this study led to a conclusion that the provision of various concentrations of
decoction of tempuyung leaves could not lower the cholesterol level in rats.