Sintesis Senyawa 4 Formil 2 Metoksifenil 3,4,5 Trihidroksibenzoat Melalui Pemanasan
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Gallic acid and vanillin are medicines that have anticancer potency of synergism, if both of them were reacted in order to get new compound and to have a better activity. Its docking study expressed a better value than native ligand of receptor. The resultis expected to have a positive correlation with biological activity. Synthesis of gallicderivatives had been donefrom gallic acid and vanillin by reacting sodium vanillate with gallic acid at 40°C. The product was tested by chromatographyanalyzes, melting point tester and its IR spectrum using FTIR. The white powder yieldobtained was 26.88%. Its chromatogram showed the formation of a new compound at Rf 0.5. The test results showed its IR spectrum of ester group at wavelength number of 1280 to 1188cm-1. It can be concluded that synthesis of gallic or 4-formyl-2- methoxyphenyl-3,4,5-trihidroxybenzoichad apparently success by heating at 40 derajat C.