Cytotoxic Effect of Etanolic Extract of Ageratum conyzoides, L Against HeLa Cell Line

Abstract

In developed countries, cancer represents the second death cause after cardiovascular disease. In Indonesia, cervix cancer represents the most cancer case in women. Continuous efforts to find the effective cancer drugs with less side effects are still being conducted. One of the ways for getting that purpose is by digging the source of nature vegetation owning potency as anticancer. The aim of this research was to investigate anticancer activity from Ageratum conyzoides, L leaves. The method used was cytotoxicity assay to HeLa cell line, and the cytotoxicity was determined by cell viability method. The number of viable and nonviable cell was counted by direct counting method using trypan blue exclusion. The cytotoxicity test revealed that the LC50 value was 855 µg/ml.