Radioprotective of Roselle Tea in Recurrent Radiodiagnostic Ionizing Radiation on Peripheral Hemogram Characteristics

Abstract

The aim of this study was to describe peripheral hemogram characteristics of mice treated with Roselle tea prior to exposure of recurrent radiodiagnostic ionizing radiation. Eighteen adult ddy male mice of Mus musculus were divided into three groups, i.e. control group (K, n=6), ionizing radiation group (P, n=6), and tea of roselle radiation group (RT, n=6). Blood samples were collected from blood venous at sinus retroorbitalis of anesthetized mice. These blood samples were examined for the numbers of leucocyte (WBC), erythrocyte (RBC), hemoglobin (Hb), hematocrit (PCV), RBC volume (MCV), Hb weight (MCH), and Hb concentration (MCHC). Blood samples were collected from mice which had been exposed of ionizing radiation for 2 weeks and 4 weeks periods. The result showed that there were no significant differences (P>0.05) on WBC, MCH, and MCHC. However, we found differences (P<0.05) on hematology characteristics for RBC, Hb, PCV, and MCV of mice after 2 weeks exposure of ionizing radiation.