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KONTROL CERDAS NYERI SECARA TRANSDERMAL MENGGUNAKAN BAHAN KAYA FLAVONOID (B. BALSAMIFERA) DAN MONOTERPEN

dc.contributor.authorYaminulloh, Sholeh
dc.contributor.authorMustika Ratna Aulia, Putri
dc.contributor.authorDwi Noor Anggraeni, Radhita
dc.contributor.authorFikri Firdaus Bakri, Dzaki
dc.contributor.authorDwi Autarina Ardiyanti, Laras
dc.date.accessioned2016-10-21T08:45:56Z
dc.date.available2016-10-21T08:45:56Z
dc.date.issued2016-08-27
dc.identifier.citationBacker, C.A.R.C Bakhuizen Van Den Brink J.R. 1968. Flora of Java. Walters-Noordholf N.V, Groningen-The Netherlands CGGJ Van Steenis, 1997. Flora Untuk Sekolah Di Indonesia. Jakarta : PT. Pramadya Paramita. Dalimartha, S. dan Soedibyo, M., 1999. Awet Muda Dengan Tumbuhan Obat dan Diet Supleme. Trubus Agriwidya, Jakarta. hal. 36-40. Damron, WS., 2003. Introduction to Animal Science: Biological, Industry Perspective. Prentice Hall, New Jersey. Farrel, D. J. & Y. C. Rahardjo. 1984. Potensi ternak kelinci sebagai penghasil daging. Balai Penelitian Ternak Bogor. Fazilatun N, Zhari I, Nornisah M, Mas RH (2004). Free radicalscavenging activity of organic extracts and of pure flavonoids of Blumea balsamifera DC leaves. Food Chem., 88: 243-252. Guenther, E., (1990), Minyak atsiri. Jilid IVB, Penerjemah S. Ketarendan R. Mulyono, Jakarta, Universitas Indonesia. Handayani ,Prima Astuti dan Eqi Rosyana Juniarti. 2012. Jurnal Bahan Alam Terbarukan. .EKSTRAKSI MINYAK KETUMBAR (Coriander Oil) DENGAN PELARUT ETANOL DAN n-HEKSANA .1(1)3-5. International Association for the Study of Pain (IASP) (1979) Pain terms: a list with definitions and notes on usage. Pain 6, 249-252. James David A. Jr, Xiaogang Wang (2015). Control of pain with topical plant medicines. Asian Pac J Trop Biomed ; 5(4): 268-273. Jeong SH, Ryu YB, Curtis-Long MJ, Ryu HW, Baek YS, Kang JE, Lee WS, Park KH (2009). Tyrosinase Inhibitory Polyphenols from Roots of Morus lhou. J. Agric. Food Chem., 57: 1195-1203. Katno, Katno, dkk. 2009. JurnalTumbuhanObatIndonesia.UJI DAYA HAMBAT EKSTRAK ETANOL DAUN SEMBUNG (Blumeabalsamifera(L.) DC.) TERHADAP PERTUMBUHAN MIKROBA E. coli, S .aureus DAN C. albicans.2(1)34-35 Khan, Shahzad. Et al.(2012). International Journal of Management and strategy.Determinants of customer satisfaction in fast food industry.,3:1-15 Mardjono, M., dan Sidharta, P.,2008.Mekanisme Trauma Susunan Saraf Pusat. Dalam : Mardjono, M., dan Sidharta, P. Neurologi Klinis Dasar. Jakarta : Dian Rakyat, 250 - 260. Muhlish, Fauziah, 1999. Tanaman Obat Keluarga, . Penebar Swadaya, Jakarta. Mutmainah, Rina S., Nuning R., dkk. Gastroprotective effects of combination of hot water extracts of turmeric (Curcuma domestica L.), cardamom pods (Ammomum compactum S.) and sembung leaf (Blumea balsamifera DC.) against aspirin-induced gastric ulcer model in rats. Asian Pac J Trop Biomed 2014; 4(Suppl 1): S500-S504 Norikura T, Kojima-Yuasa A, Shimizu M, Huang X, Xu S, Kametani S, Rho S, Kennedy DO, Matsui-Yuasa I (2008). Mechanism of growth inhibitory effect of Blumea balsamifera extract in Hepatocellular Carcinoma. Biosci. Biotechnol. Biochem., 72: 1183- 1189 Pudjiastuti, B., Dzulkarnain, dan Y. Astuti. 1996. Uji analgetik infus daun sembung (Blumea Balsamifera DC.) pada mencit putih. Cermin Dunia Kedokteran 28: 34-36. Retnowati, Rurini, dkk, 2013. ISOLASI DAN KARAKTERISASI TERHADAP MINYAK MINT DARI DAUN MENTHA ARVENSIS SEGAR HASIL DISTILASI UAP- AIR. Malang: KIMIA.STUDENTJOURNAL, Vol. 2, No. 2, pp.574-579. (Online)(http://kimia.studentjournal .ub.ac.id/index.php/jikub/article/vie w/374,diakses tanggal 9 Okotober 4 April 2015 Reijal.2008.Daun SembungBlumeae Balsamifera.http://reijal.blogspot.c om/2008/12/daun-sembung- blumae-balsamifera.html.diakses tanggal 10 september 2015 jam 16.00 WIB Ruangrungsi N, Tappayuthpijaran P, Tantivatana P (1981). Traditional medicinal plants of Thailand I. Isolation and structure elucidation of two new fla s, (2R,3R)- dihydroquercetin 10 thyl ether and (2R,3R)-dihydroquercetin-4‟,7- dimethyl ether from Blumeabalsamifera. J. Nat. Prod., 44: 541-545.\ Safita S.H., Artha W.U., Latifatul I (2012). Plester Ekstrak Etanol Daun Dan Batang Talas (Colocasia esculenta) Sebagai Alternatif Obat Luka Alami. Sudharmayanti, L. Eka Rica . 2004. Uji Efek Ekstrak Daun Sembung (Blumea balsamifera L.DC.) Dosis 7 g/kg BB terhadap Bobot Granuloma pada Tikus Putih Betina Inflamasi Akibat Pektin. Skripsi. Fakultas Farmasi Universitas Surabaya, Surabaya. Supriadi 2001. Tumbuhan Obat Indonesia: Penggunaan dan Khasiatnya. Jakarta. Yayasan Obor Indonesia: xi-xxvii Wilmana, P.F.1995. Analgesik Antipiretik Antiinflamasi Non Steroid dan Obat Piri. Dalam Ganiswara, S.G. (Ed). Farmakologi dan Terapi. Edisi 4. Jakarta : Fakultas Kedokteran Universitas Indonesia.in_ID
dc.identifier.issn2407-9189
dc.identifier.urihttp://hdl.handle.net/11617/7728
dc.description.abstractThe treatment of pain there are many drawbacks such leave interfere with liver function, renal, gastrointestinal, and blood clots, and can cause aplastic anemia that required drug consumption ismore practical. (Wilmana, 1995). Purpose: This study aimed to formulate anti-pain drugs transdermally using ethanol extract sembung and monoterpenes safer with minimal side effects. Methods:In this study, transdermal patch preparation with the composition of HPMC, PVP, glyserin, ethanol, and the extract condensed with 7 x 10 cm. In testing the power of analgesic used test animals Wistar male rats strain as much as 20 tails were divided into 5 groups. Each distinguished its extract concentration and given negative control (alcohol) as well as the positive control. After 10 minutes, all the test animals are inoculated intraperitoneally with 1% acetic acid as the induction of pain. During the first hour, all the test animals were observed and recorded thenstretchs calculated % analgesic strenght. Results and conclusions: The provision of 1% acetic acid intraperitoneally effects of pain characterized by stretching. Analysis% analgesic strenght after T test showed that the patch formulation A on male Wistarrats strain can lower pain response significantly compared to the positive control group (p <0.05). This formulation has great potential to be developed as a pain killer in the future.in_ID
dc.language.isoidin_ID
dc.publisherSTIKES Muhammadiyah Pekajanganin_ID
dc.subjectpainin_ID
dc.subjecttransdermalin_ID
dc.subjectsembungin_ID
dc.subjectmonoterpenesin_ID
dc.titleKONTROL CERDAS NYERI SECARA TRANSDERMAL MENGGUNAKAN BAHAN KAYA FLAVONOID (B. BALSAMIFERA) DAN MONOTERPENin_ID
dc.typeArticlein_ID


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