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Prediksi 3d-Molekular Aktivitas Turunan Senyawa Polihidroksi Zerumbon Terhadap Glikogen Sintase Kinase-3 Beta (GSK-3B) Menggunakan Dock6
(LPPM Universitas Muhammadiyah Semarang, 2016-02)
Insulin resistance causes 90% of type 2 diabetes mellitus (DM) cases and this is due to an increase in the activity of glycogen synthase kinase-3 (GSK-3). Dephosphorylation and activation of glycogen synthase ...
Pemodelan In Silico Inhibitor Gsk-3β (CHIR99021, CHIR98014, AZD1080, TWS11) Dan Turunan Zerumbon Terhadap Protein 4PTG Melalui Perangkat Lunak PYR
(STIKES Muhammadiyah Pekajangan, 2016-08-27)
Glycogen synthase kinase-3 (GSK-3) is a serine / threonine kinase whose activity is related to various diseases such as diabetes, cancer, Alzheimer's, and stroke. In silico method is one of the choice to study and look for ...
Kajian Docking Molekular Pada Binding Site Pocket Dari Flavopiridol Dalam Menghambat Glikogen Fosforilase Menggunakan Pyrx-Autodock-Vina
(STIKES Muhammadiyah Pekajangan, 2016-08-27)
nhibition of the enzyme glycogen phosphorylase which break down glycogen into glucose 1- phosphate (glycogenolysis) is a target in the treatment of type 2 diabetes milletus. Interaction mechanism between glycogen phosphorylase ...
Identifikasi Agen Antidiabetes Melalui Jalur Penghambatan Aldose Reductase Menggunakan Pyrxdengan Empat Algoritma Molecular Docking
(STIKES Muhammadiyah Pekajangan, 2016-08-27)
Aldosereductaseisaldo-ketoreductaseenzyme that convert glucoseto sorbitol and fructosebypolyolpathway. Accumulation of sorbitol andoxidative stress dueto changes in the ratio of NADPH/NADP+ and NADH/NAD+ cause some ...
Sintesis Senyawa (2E)-3-Fenilprop-2-Enoil 3,4,5- Trihidroksibenzoat Dengan Menggunakan Microwave
(STIKES Muhammadiyah Pekajangan, 2016-08-27)
A drug compounds can be obtained through synthesis by modifying the structure of potential. Gallic acid and cinnamaldehyde alleged to have potent antioxidant activity. If two compounds are combined is expected to form a ...
Sintesis Senyawa 4 Formil 2 Metoksifenil 3,4,5 Trihidroksibenzoat Melalui Pemanasan
(STIKES Muhammadiyah Pekajangan, 2016-08-27)
Gallic acid and vanillin are medicines that have anticancer potency of synergism, if both of them were reacted in order to get new compound and to have a better activity. Its docking study expressed a better value than ...