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dc.contributor.authorSantosa, Budi
dc.date.accessioned2015-02-04T02:25:53Z
dc.date.available2015-02-04T02:25:53Z
dc.date.issued2015-01-24
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dc.identifier.issn2407-9189
dc.identifier.urihttp://hdl.handle.net/11617/5182
dc.description.abstractZinc supplementation increases metallothionein was binding of lead, so the impact exposed to lead that cause hematopoesis inhibition and G-6PD deficiency at rats can be inhibited. Objective: Zn supplementation can repair hematopoesis at rats exposed to lead. The research method was randomized post-test only control group design. Twenty eight rats are divided 4 groups: one control group, three treatment groups supplemented zinc 0.2; 0.4; 0.8 mg via sonde until 3 week. Control and treatment exposed Pb 0.5 g/kg/Weight/day until 13 week . End of week 13 examined Hb using Cyanmethemoglobin and erythrocytes count using hematology analyzer, and reticulocytes using BCB staining . Differences between groups of hemoglobin , erythrocytes ,reticulocytes test used one way ANOVA and Bonferroni. Results showed levels of hemoglobin and erythrocytes increased count of treatment group to the control group , while the number of reitukolosit decreased. Based on statistical test of differences between treatment groups with the control of the 2nd and 3rd ( p = 0.00 ) . Conclusion , zinc supplementation of 0.4 and 0.8 mg able to repair hematopoesis in rats exposed to leaden_US
dc.publisherUniversitas Muhammadiyah Surakartaen_US
dc.subjecthematopoesisen_US
dc.subjectexsposed to leaden_US
dc.subjectsuplementation Znen_US
dc.titleVariasi Dosis Suplementasi ZN Memperbaiki Hematopoesis pada Tikus yang Terpajan Plumbum (PB)en_US
dc.typeArticleen_US


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