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Potensi Efek Antipiretik Daun Kemangi (Ocimum sanctum L.) dan Daun Dewa (Gynura pseudochina (L) D.C)

dc.contributor.authorSutrisna, EM
dc.contributor.authorWahyuni, Arifah Sri
dc.contributor.authorSetyowati, Sri
dc.contributor.authorTriwinarsih, Irna
dc.date.accessioned2013-07-02T03:27:20Z
dc.date.available2013-07-02T03:27:20Z
dc.date.issued2009-12
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Int J Clin Pharmacol Ther Toxicol. 26 (4):176184. Perry LM.,1980, Medicinal Plants of East and South East Asia: Attributed Properties Puspangdan P, and Sobti SN., 1977, Medicinal Properties of Ocimum (Tulsi) species and some recent investigation of their efficacy. Ind. Drugs, 14 (11):207 Rivai,H., Nurdin,H., Suyani,H., dan Bakhtiar,A., 2011, Karakterisasi ekstrak daun dewa (Gynura pseudochina (L.) DC) dengan kromatografi cair kinerja tinggi, Jurnal Farmasi Indonesia Vol. 5 No. 3: 134 -141 Sayuthi, D., Darusman, L.K., Suparto, I.H., Imanah A., 2000, Potensi senyawa bioaktif daun dewa (Gynura pseudochina (Linn.) DC. sebagai antikanker, Buletin Kimia 1(1): 23-29. Sayuthi D. 2001, Ekstraksi, fraksinasi, karakterisasi dan uji hayati in vitro senyawa bioaktif daun dewa (Gynura pseudochina (Linn.) DC. Sebagai antikanker. Buletin Kimia; 1(2): 75-79. Singh N. & Misra N., 1987, Stress disease and their possible remedy by antistress drugs (Adaptogens/ Staminators) of plant origin. Physiology of Human Performance. In Proc Nat Symp Physiol Hum Perfor. (Sawhney RC, Sridharan K and Selvamurthy W, eds) Publisher: Defence Institute of Physiology and Allied Science, Defence Research and Development Organization (DRDO), Govt. of India, Delhi, pp. 89-94. Singh N. A., 1986, Pharmaco- clinical evaluation of some ayurvedic crude plant drugs as antistress agents and their usefulness in some stress disease of man.Ann. Nat Acad Ind Med. 2(1):14- 26. Singh, S., Taneja, M, and Majumdar DK., 2007, Biological activities of Ocimum sanctum L. fixed oil -an Overview. Indian J. Exp. Biol. 45(5): 403-412. Singh SP, and Singh N.,1981, Experimental evaluation of adaptogenic properties of Ocimum sanctum. Ind. J. Pharmacol. 10: 74. 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dc.identifier.issn1411–4283
dc.identifier.urihttp://hdl.handle.net/11617/3197
dc.description.abstractSecara empiris daun Kemangi (Ocimum sanctum L.) dan daun Dewa (Gynura pseudochina (L) D.C) digunakan untuk menurunkan demam. Tujuan penelitian ini untuk membuktikan secara ilmiah efek tersebut dan membandingkan kekuatan kedua tanaman tersebut. Jenis penelitian merupakan kuasi eksperimental dengan rancangan acak lengkap pola searah. Sebanyak empat puluh ekor mencit jantan galur Swiss dibagi dalam 8 kelompok. Setiap kelompok terdiri dari 5 mencit. Semua mencit diinjeksi tetanus toksoid dosis 0,3 ml/23,67 gBB ip sebagai penginduksi demam. Enam puluh menit kemudian diberi perlakuan sesuai kelompoknya. Kelompok I diberi WFI 0,5 mL/20g mencit. Kelompok II diberi parasetamol dosis 65 mg/kgbb. Kelompok III,IV dan V diberi infusa daun kemangi dosis berturut-turut 1,25; 2,5 dan 10 g/kgbb. Kelompok VI, VII dan VIII diberi infusa daun dewa dosis berturut-turut 1; 2 dan 4 g/kgbb. Pengukuran suhu dilakukan tiap 30 menit sampai menit 210. Dihitung selisih penurunan suhu dan persen daya antipiretiknya. Data dianalisis dengan analisis varian satu jalan dilanjutkan dengan Tuckey HSD dengan taraf kepercayaan 95%. Hasil penelitian menunjukkan bahwa Infusa daun kemangi (Ocimum sanctum L.) dosis 5 g/kgbb, daun Dewa (Gynura pseudochina (L) D.C) dosis 1; 2 dan 4g/kgbb mempunyai daya antipiretik yang sebanding dengan parasetamol dosis 65 mg/kgbb. Potensi antipiretik daun Dewa (Gynura pseudochina(L) D.C)) lebih besar daripada Kemangi (Ocimum santum L.)en_US
dc.publisherFarmasi UMSen_US
dc.subjectantipiretiken_US
dc.subjectOcimum sanctum Len_US
dc.subjectGynura pseudochina (L) D.C)en_US
dc.titlePotensi Efek Antipiretik Daun Kemangi (Ocimum sanctum L.) dan Daun Dewa (Gynura pseudochina (L) D.C)en_US
dc.typeArticleen_US


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