Browsing Prosiding University Research Colloquium by Author "Santoso, Broto"
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Analisis Profil Metabolit Sekunder Ekstrak Lempuyang Emprit dengan Kromatografi Gas-Spekstroskopi Massa
Hanwar, Dedi; Suhendi, Andi; Trisharyanti, Ika; Santoso, Broto; Safitri, Meisa; Haryoto (Universitas Muhammadiyah Surakarta, 2015-01-24)Lempuyang emprit (Zingiber amaricans Bl) is one of the plants species that contain secondary metabolites that are important in diseases treatment. This study was conducted to determine the secondary metabolites contained ... -
Identifikasi Agen Antidiabetes Melalui Jalur Penghambatan Aldose Reductase Menggunakan Pyrxdengan Empat Algoritma Molecular Docking
Salim Maulana, Agus; Wulansari, Kiki; Anwar Zhelsiana, Devy; Sri Sulasmi, Wiwin; Santoso, Broto (STIKES Muhammadiyah Pekajangan, 2016-08-27)Aldosereductaseisaldo-ketoreductaseenzyme that convert glucoseto sorbitol and fructosebypolyolpathway. Accumulation of sorbitol andoxidative stress dueto changes in the ratio of NADPH/NADP+ and NADH/NAD+ cause some ... -
Kajian Docking Molekular Pada Binding Site Pocket Dari Flavopiridol Dalam Menghambat Glikogen Fosforilase Menggunakan Pyrx-Autodock-Vina
Farid Yoga Pratama, Miftah; Rosyad Abidi, Subhan; Arum Firdaus, Khisma; Fitri Aulia, Alif; Santoso, Broto (STIKES Muhammadiyah Pekajangan, 2016-08-27)nhibition of the enzyme glycogen phosphorylase which break down glycogen into glucose 1- phosphate (glycogenolysis) is a target in the treatment of type 2 diabetes milletus. Interaction mechanism between glycogen phosphorylase ... -
Pemodelan In Silico Inhibitor Gsk-3β (CHIR99021, CHIR98014, AZD1080, TWS11) Dan Turunan Zerumbon Terhadap Protein 4PTG Melalui Perangkat Lunak PYR
Roro Shafira Meisy Sudarsono, Raden; Dwi Puspita Sari, Hana; Beny Santosa, Agung; Ayu Resti Lailya Anggraini, Dyah; Santoso, Broto (STIKES Muhammadiyah Pekajangan, 2016-08-27)Glycogen synthase kinase-3 (GSK-3) is a serine / threonine kinase whose activity is related to various diseases such as diabetes, cancer, Alzheimer's, and stroke. In silico method is one of the choice to study and look for ... -
Prediksi 3d-Molekular Aktivitas Turunan Senyawa Polihidroksi Zerumbon Terhadap Glikogen Sintase Kinase-3 Beta (GSK-3B) Menggunakan Dock6
Santoso, Broto; Hanwar, Dedi; Suhendi, Andi (LPPM Universitas Muhammadiyah Semarang, 2016-02)Insulin resistance causes 90% of type 2 diabetes mellitus (DM) cases and this is due to an increase in the activity of glycogen synthase kinase-3 (GSK-3). Dephosphorylation and activation of glycogen synthase ... -
Sensor Kolorimetrik Berbasis Agregasi Nanopartikel Emas dan Polimer Responsif pH Poli(Asam Akrilat)
Wikantyasning, Erindyah R; Rizqiyana, Fika; Santoso, Broto; Suprapto (Universitas Muhammadiyah Surakarta, 2015-01-24)The synthesis and pH-sensitive behavior of poly(acrylic acid) (PAA) and gold nanoparticles (AuNPs) are presented. Gold nanoparticles was synthesized by Turkevich method and analyzed by TEM and UV-Vis spectrophotometer ... -
Sintesis Senyawa (2E)-3-Fenilprop-2-Enoil 3,4,5- Trihidroksibenzoat Dengan Menggunakan Microwave
Kuswandi, M.; Kusumaningtyas, Erwinda; Santoso, Broto (STIKES Muhammadiyah Pekajangan, 2016-08-27)A drug compounds can be obtained through synthesis by modifying the structure of potential. Gallic acid and cinnamaldehyde alleged to have potent antioxidant activity. If two compounds are combined is expected to form a ... -
Sintesis Senyawa 4 Formil 2 Metoksifenil 3,4,5 Trihidroksibenzoat Melalui Pemanasan
Kuswandi, M.; Krismiyati, Dwi; Santoso, Broto (STIKES Muhammadiyah Pekajangan, 2016-08-27)Gallic acid and vanillin are medicines that have anticancer potency of synergism, if both of them were reacted in order to get new compound and to have a better activity. Its docking study expressed a better value than ...